The Interplay Between Osteoporosis and Peri-implantitis: Implications for Dental Implant Therapy

Abstract

Osteoporosis, a systemic skeletal disorder characterized by reduced bone density and increased fracture risk, has been implicated in the pathogenesis of peri-implantitis, an inflammatory condition affecting dental implants. This review explores the relationship between osteoporosis and peri-implantitis, focusing on potential mechanisms linking these two conditions and their implications for dental implant therapy. Evidence suggests that osteoporosis may predispose individuals to peri-implant complications by compromising bone quality and quantity, altering the bone-implant interface, and modulating the host immune response. Conversely, peri-implantitis may exacerbate bone loss in osteoporotic patients, further compromising implant stability and longevity. The management of peri-implantitis in patients with osteoporosis poses unique challenges, necessitating a multidisciplinary approach that considers both systemic and local factors. Strategies for preventing and treating peri-implantitis in osteoporotic individuals may include optimizing bone health, modifying implant placement techniques, and implementing tailored therapeutic interventions. Further research is needed to elucidate the complex interplay between osteoporosis and peri-implantitis and develop evidence-based guidelines for managing dental implant complications in this patient population.